Look here why is PGT the best option for you,

• 01PGT helps to detect genetic disorders or chromosomal defects in embryos before they are transferred into the uterus, reducing the chances of passing on a genetic disorder to your child.
• 02It is a non-invasive procedure that includes removing one or more cells from each embryo, which poses minimal risk to the embryo.
• 03PGT can help couples with a high risk of passing on genetic disorders to pick healthy embryos, increasing their probability of having a healthy baby.
• 04It allows for personalized treatment plans and can higher the success rates of IVF treatments and reducing treatment duration, treatment cost and emotional frustration.

Here  are  some  genetic  diseases  that  can  be  prevented  or  identified  using  Preimplantation  Genetic Testing (PGT):

• 01
  

  Cystic Fibrosis:

  a genetic defect that hinders the respiratory, digestive, and reproductive systems.

• 02
  

  Sickle cell anemia:

  an inherited blood disorder that affects the shape and function of red blood cells.

• 03
  

  Thalassemia:

  an inherited blood disorder that impairs the production of red blood cells.

• 04
  

  Huntington’s disease:

  a progressive brain disorder that impedes movement, cognition, and behavior.

• 05
  

  Tay-Sachs disease:

  an uncommon genetic disorder that hinders the nervous system and causes developmental delay, muscle fragility, and vision and hearing loss.

• 05
  

  Hemophilia:

  a genetic disorder that affects the blood’s capability to clot properly, leading to extreme bleeding and bruising.

• 06
  

  Fragile X syndrome:

  a genetic disorder that occurs intellectual and developmental disabilities and behavioural challenges.

  PGT can also be used to identify chromosomal disorders such as Down syndrome, Turner syndrome, and Klinefelter syndrome. Additionally, PGT can be used to identify specific genetic mutations that highers the risk of cancer, such as BRCA1 and BRCA2, Lynch syndrome.

Look here the different types of PGT ,

• 01
  

  PGT-A (Aneuploidy Screening):

  PGT-A is used to screen embryos for chromosomal abnormalities, which can cause conditions such as Down syndrome, Turner syndrome, and Klinefelter syndrome. This type of PGT can help determine the embryos having too many or too few chromosomes, which can result in implantation failure or miscarriage. PGT-A is often recommended for couples who have had multiple failed IVF cycles or recurrent miscarriages.

• 02
  

  PGT-M (Monogenic/Single Gene Disorders):

  PGT-M is used to identify single gene disorders, which are caused by mutations in a specific gene. This type of PGT can help identify embryos that are carriers of a specific genetic disorder, such as cystic fibrosis or sickle cell anemia. PGT-M is typically recommended for couples who have known genetic disorders or who have a family history of a genetic disorder.

• 03
  

  PGT-SR (Structural Rearrangements):

  PGT-SR is used to identify embryos that have chromosomal rearrangements, such as translocations or inversions. These chromosomal disorders can cause miscarriage, stillbirth, or the birth of a child with a genetic disorder. PGT-SR can help identify embryos that are carriers of chromosomal rearrangements, which can increase the chances of a successful pregnancy.

• 04
  

  PGT HLA (Tissue Typing for Stem Cell Therapy):

  PGT HLA is used to identify embryos that are a genetic match for a sibling with a specific disease, such as leukemia or thalassemia. This type of PGT can help create a donor sibling who can provide stem cells for transplant to the affected sibling. PGT HLA is typically recommended for couples who have a child with a specific disease that can be treated with stem cell therapy.

It’s important to note that not all fertility clinics in Abu Dhabi offer all types of PGT, and the specific tests and technologyavailable will depend on the clinic’s expertise and resources. Additionally, PGT is not always foolproof, and there is always a chance of new genetic mutations occurring or the failure of the chosen embryos to implant. However, PGT is a powerful tool that can help many couples reduce the risk of passing on genetic diseases to their children and improves the chances of a successful pregnancy.

Here’s an overview of how Pre-implantation Genetic Testing (PGT) works:

• 01In vitro fertilization (IVF) is used to create embryos outside of the body.
• 02On the 5th day of development, when the embryos are at blastocyst stage, one or more cells are retrieved from each embryo.
• 03The retrieved cells are then sent to a laboratory for genetic analysis, which can include PGT-A (aneuploidy screening), PGT-M (monogenic/single gene disorders), PGT-SR (structural rearrangements), or PGT HLA (tissue typing for stem cell therapy).
• 04After the genetic analysis is complete, the fertility specialist will select the healthiest embryos for transfer to the uterus.
• 05The chosen embryos are then implanted into the uterus in the fresh menstrual cycle.

Dr.  Ripal  Madnani  is  a  leading  fertility  doctor  in  Abu Dhabi  who  specializes  in  PGT  and  other  infertility  treatments.  At  her  Fertility  Center  in  Abu Dhabi,  she  uses  the  latest  technology  and  methods  to  ensure  the  best  possible  success rates for her  patients.  Dr.  Madnani  and  her  team  provide  personalized  care  and  support  throughout  the journey of fertility  treatment,  ensuring  that  patients  feel  comfortable  and  informed  every  step  of  the  way.  If  you  are  considering  PGT  or  other  infertility  treatments,  Dr.  Madnani  is  an  excellent  choice  for  high-quality care and successful outcomes.

 “Don’t wait to make an appointment for PGT consultation with our Expert!”