Ovarian PRP

Suffering from poor ovarian reserve or low AMH at young or middle age, don’t be disheartened, you still can have few options available to rejuvenate your ovary.

Age-related decline in fertility and premature loss of ovarian reserve has become a major concern for the fertility specialist as the average age of conceiving first child has dramatically increased over past few years. Looking to the physiology, most follicles in the human ovary remain dormant throughout the female life span and gradually become atretic. However, the ovary holds oogonial stem cells, which may have the ability to differentiate into functional follicles.

The crucial question for reproductive medicine specialist is how to reactivate some of the presumed “ovarian reserve” in those females with premature follicular depletion or those who wish to become pregnant at advanced age. If you are looking for most effective PRP treatment in Abu Dhabi then you must consult Dr. Ripal Madnani.

Platelet rich plasma (PRP) is a blood-derived product, characterized by high concentrations of growth factors and chemokines. PRP is produced by centrifuging a small quantity of the patient’s own blood and extracting the active, platelet-rich fraction. The platelet-rich fraction is injected to the human body organs. More studies and clinical trials are needed before recommending PRP as a standard treatment option, despite the fact that it is used therapeutically in a variety of medical specialties, from orthopedics to plastic surgery. This is due to PRP’s putative ability to stimulate and facilitate cell proliferation, which in turn leads to tissue differentiation and regeneration.

In the context of reproductive medicine, PRP has been proposed to increase pregnancy rates after flushing uterine cavity in women with recurrent implantation failure or thin endometrium. In cases of idiopathic poor ovarian reserve, premature ovarian insufficiency, or ovarian depletion because of advanced maternal age, intra-ovarian injection of PRP has been recommended to awaken dormant prenatal ovarian follicles prior to IVF treatment.

The effectiveness and safety of intra-ovarian PRP injection for treating premature ovarian failure, and more specifically, not in patients with depleted ovarian reserve/poor ovarian response (POR), who make up a significant portion of patients undergoing assisted reproduction, have not yet been evaluated in a randomised placebo-controlled trial. But, it has been taken into consideration for the group of women who do not want to give up and want to have their own genetic child.

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